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Journal Articles

Microstructural Parameter-Based Modeling for Transport Properties of Collagen Matrices

Seungman Park, Catherine Whittington, Sherry L. Voytik-Harbin, Bumsoo Han

J Biomech Eng. June 2015, 137(6): 061003.

Paper No: BIO-14-1479

DOI: https://doi.org/10.1115/1.4029920

Published Online: June 1, 2015

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Topics: Permeability, Porosity, Fluids, Computational methods, Modeling, Particulate matter

Proceedings Papers

Freezing-Induced Cell-Fluid-Matrix Interaction in Engineered Tissue

Junkyu Jung, Ka Yaw Teo, J. Craig Dutton, Bumsoo Han

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 895-896, June 25–29, 2008

Paper No: SBC2008-192208

DOI: https://doi.org/10.1115/SBC2008-192208

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Topics: Biological tissues, Fluids, Freezing, Biophysics, Cryonics, Design, Performance, Thawing

Proceedings Papers

Freezing-Assisted Intracellular Drug Delivery to Multi-Drug Resistant Cancer Cells

Ka Yaw Teo, Bumsoo Han

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 271-272, June 25–29, 2008

Paper No: SBC2008-192373

DOI: https://doi.org/10.1115/SBC2008-192373

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Topics: Cancer, Drug delivery systems, Drugs, Freezing, Cell membranes, Extruding, Pharmacokinetics, Proteins

Proceedings Papers

Spatiotemporal Temperature Measurement Using Quantum Dot Thermometry During Nanoshell Mediated Thermal Therapy

Bumsoo Han, Willard L. Hanson, Karim Bensalah, Altug Tuncel, Joshua Stern, Jeffrey A. Cadeddu

Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 97-98, June 25–29, 2008

Paper No: SBC2008-192658

DOI: https://doi.org/10.1115/SBC2008-192658

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Topics: Patient treatment, Quantum dots, Spatiotemporal phenomena, Temperature measurement, Tumors, Biological tissues, Surgery

Proceedings Papers

Development of Quantum Dot-Embedded Nanoparticles for Biothermal Imaging

Willard L. Hanson, Nancy L. Michael, Choong-Un Kim, Bumsoo Han

Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 75-76, June 20–24, 2007

Paper No: SBC2007-176185

DOI: https://doi.org/10.1115/SBC2007-176185

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Topics: Imaging, Nanoparticles, Biological tissues, Surgery, Cancer, Temperature, Tumors, Blood vessels, Fluorescence, Freezing

Proceedings Papers

Freezing Induced Microstructural Change of Collagen Matrix

Bumsoo Han, Jeffrey D. Miller, Jun K. Jung

Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 1051-1052, June 20–24, 2007

Paper No: SBC2007-175251

DOI: https://doi.org/10.1115/SBC2007-175251

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Topics: Freezing, Biological tissues, Biomaterials, Arrhythmias, Biomedicine, Cancer, Cryonics, Mechanical properties, Preservation, Scanning electron microscopy

Journal Articles

Measurement of Spatiotemporal Intracellular Deformation of Cells Adhered to Collagen Matrix During Freezing of Biomaterials

Soham Ghosh, J. Craig Dutton, Bumsoo Han

J Biomech Eng. February 2014, 136(2): 021025.

Paper No: BIO-13-1430

DOI: https://doi.org/10.1115/1.4026180

Published Online: February 5, 2014

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Topics: Biological tissues, Deformation, Freezing, Particulate matter, Spatiotemporal phenomena, Biomaterials

Proceedings Papers

Spatiotemporal Intracellular Deformation of Cells During Freezing-Induced Cell-Fluid-Matrix Interactions

Soham Ghosh, J. Craig Dutton, Bumsoo Han

Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT49A006, June 26–29, 2013

Paper No: SBC2013-14673

DOI: https://doi.org/10.1115/SBC2013-14673

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Topics: Deformation, Fluids, Freezing, Spatiotemporal phenomena, Biological tissues, Biomaterials, Tissue engineering, Adhesion, Biology, Biomedicine

Proceedings Papers

Visualizing Chondrocyte Mechanotransduction in 3D

Qiaoqiao Wan, Eunhye Cho, Seungman Park, Bumsoo Han, Hiroki Yokota, Sungsoo Na

Paper No: SBC2013-14484

DOI: https://doi.org/10.1115/SBC2013-14484

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Topics: Chondrocytes, Cartilage, Maintenance, Stress, Adhesion, Biosensors, Energy transformation, Enzymes, Fluorescence, Linkages

Proceedings Papers

Tumor-on-Chip: Simulation of Complex Transport Around Tumor

Bongseop Kwak, Kinam Park, Bumsoo Han

Proc. ASME. NEMB2013, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, V001T02A006, February 4–6, 2013

Paper No: NEMB2013-93314

DOI: https://doi.org/10.1115/NEMB2013-93314

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Topics: Simulation, Tumors, Biological tissues, Blood, Bridges (Structures), Drugs, Fluid pressure, Microfluidics, Nanoparticles, Performance

Proceedings Papers

Effects of Freezing on Collagen Nanoscale Structure in Engineered Tissues

Altug Ozcelikkale, Yan Li, Xianfan Xu, Bumsoo Han

Proc. ASME. NEMB2013, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, V001T03A001, February 4–6, 2013

Paper No: NEMB2013-93125

DOI: https://doi.org/10.1115/NEMB2013-93125

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Topics: Biological tissues, Freezing, Nanoscale phenomena, Biomaterials, Cryonics, Performance, Physiology

Proceedings Papers

Nanoscale Fluid-Structure Interactions in Cytoplasm During Freezing

Altug Ozcelikkale, Bumsoo Han

Proc. ASME. IMECE2012, Volume 2: Biomedical and Biotechnology, 711-716, November 9–15, 2012

Paper No: IMECE2012-88161

DOI: https://doi.org/10.1115/IMECE2012-88161

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Topics: Fluid structure interaction, Freezing, Nanoscale phenomena, Space, Cryobiology

Proceedings Papers

Spatiotemporal Deformation of Engineered Tissue During Freezing

Ka Yaw Teo, J. Craig Dutton, Bumsoo Han

Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 205-206, June 17–21, 2009

Paper No: SBC2009-206367

DOI: https://doi.org/10.1115/SBC2009-206367

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Topics: Biological tissues, Deformation, Freezing, Spatiotemporal phenomena, Cryonics, Preservation, Biomaterials, Storage

Proceedings Papers

Tissue-Light Interaction During Monitoring of Thermal Lesion Using Quantum Dot Mediated Fluorescence Thermometry

Willard Hanson, Najma Abdollahzadeh, Yaling Liu, Bumsoo Han

Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 351-352, June 17–21, 2009

Paper No: SBC2009-205517

DOI: https://doi.org/10.1115/SBC2009-205517

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Topics: Biological tissues, Cancer, Energy resources, Fluorescence, Heating, Lasers, Microwaves, Patient treatment, Quantum dots, Temperature measurement

Proceedings Papers

Effects of Collagen Microstructure on the Transport Properties of Vascularized Engineered Tissues

Seungman Park, Catherine Whittington, Mervin C. Yoder, Sherry Voytik-Harbin, Bumsoo Han

Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 633-634, June 20–23, 2012

Paper No: SBC2012-80817

DOI: https://doi.org/10.1115/SBC2012-80817

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Topics: Biological tissues, Diseases, Vessels, Biopolymers, Failure, Physiology

Proceedings Papers

Role of Cells in Freezing-Induced Cell-Fluid Matrix Interactions Within Engineered Tissues

Angela Seawright, Altug Ozcelikkale, J. Craig Dutton, Bumsoo Han

Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 409-410, June 20–23, 2012

Paper No: SBC2012-80531

DOI: https://doi.org/10.1115/SBC2012-80531

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Topics: Biological tissues, Fluids, Freezing, Cryonics, Biomedicine, Preservation, Storage, Thawing, Tissue engineering

Proceedings Papers

Functional Imaging of Matrix Structure of Cryopreserved Engineered Tissues Using Back-Directional Gated Mesoscopic Imaging

Young L. Kim, Zhengbin Xu, Altug Ozcelikkale, Bumsoo Han

Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 259-260, June 20–23, 2012

Paper No: SBC2012-80692

DOI: https://doi.org/10.1115/SBC2012-80692

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Topics: Biological tissues, Imaging, Mesoscopic systems, Cryonics, Fluids, Freezing, Preservation, Tissue engineering

Proceedings Papers

Modified Challenge-Based Teaching of Biotransport Phenomena

Bumsoo Han

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 753-754, June 22–25, 2011

Paper No: SBC2011-53300

DOI: https://doi.org/10.1115/SBC2011-53300

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Topics: Biotransport, Teaching, Students, Bioengineering, Biology, Biomedical engineering, Chemical engineering, Mechanical engineering

Proceedings Papers

A Biphasic Model Illuminating Freezing-Induced Fluid-Matrix Interactions in a Tissue Equivalent

Jamie Wright, Bumsoo Han, Cheng-Jen Chuong

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 755-756, June 22–25, 2011

Paper No: SBC2011-53321

DOI: https://doi.org/10.1115/SBC2011-53321

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Topics: Biological tissues, Fluids, Freezing, Deformation, Preservation, Cryonics, Pressure, Stress, Thawing, Transients (Dynamics)

Proceedings Papers

Effects of Freezing on Cytoskeletal Structure of Fibroblasts in Engineered Tissues

Angela Seawright, Bumsoo Han

Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 915-916, June 22–25, 2011

Paper No: SBC2011-53105

DOI: https://doi.org/10.1115/SBC2011-53105

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Topics: Biological tissues, Fibroblasts, Freezing, Cryonics, Preservation, Adhesion, Drugs, Fluids, Storage, Stress

Journal citation

NARROW

Microstructural Parameter-Based Modeling for Transport Properties of Collagen Matrices

Freezing-Induced Cell-Fluid-Matrix Interaction in Engineered Tissue

Freezing-Assisted Intracellular Drug Delivery to Multi-Drug Resistant Cancer Cells

Spatiotemporal Temperature Measurement Using Quantum Dot Thermometry During Nanoshell Mediated Thermal Therapy

Development of Quantum Dot-Embedded Nanoparticles for Biothermal Imaging

Freezing Induced Microstructural Change of Collagen Matrix

Measurement of Spatiotemporal Intracellular Deformation of Cells Adhered to Collagen Matrix During Freezing of Biomaterials

Spatiotemporal Intracellular Deformation of Cells During Freezing-Induced Cell-Fluid-Matrix Interactions

Visualizing Chondrocyte Mechanotransduction in 3D

Tumor-on-Chip: Simulation of Complex Transport Around Tumor

Effects of Freezing on Collagen Nanoscale Structure in Engineered Tissues

Nanoscale Fluid-Structure Interactions in Cytoplasm During Freezing

Spatiotemporal Deformation of Engineered Tissue During Freezing

Tissue-Light Interaction During Monitoring of Thermal Lesion Using Quantum Dot Mediated Fluorescence Thermometry

Effects of Collagen Microstructure on the Transport Properties of Vascularized Engineered Tissues

Role of Cells in Freezing-Induced Cell-Fluid Matrix Interactions Within Engineered Tissues

Functional Imaging of Matrix Structure of Cryopreserved Engineered Tissues Using Back-Directional Gated Mesoscopic Imaging

Modified Challenge-Based Teaching of Biotransport Phenomena

A Biphasic Model Illuminating Freezing-Induced Fluid-Matrix Interactions in a Tissue Equivalent

Effects of Freezing on Cytoskeletal Structure of Fibroblasts in Engineered Tissues

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