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Keywords: lung
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Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2014, 136(7): 074504.
Paper No: BIO-13-1509
Published Online: May 29, 2014
... digital flexor tendons [ 7 ]. Clinical application will require development of ultrasound imaging-based methods capable of detecting such changes in lung compliance in vivo. Additionally, the ultrasound measurements performed in this study examine a small area (dependent on transducer area)—in rat lung...
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2011, 133(12): 124502.
Published Online: December 21, 2011
... of electrical charges, sizes, concentrations of the particles have been investigated. In this paper, the temperature effect on the cellular uptake of Quantum Dots (QDs) is studied experimentally. QDs are incubated with the SPCA-1 human lung tumor cells, and the nanoparticles on the cell membrane and inside...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2011, 133(11): 111005.
Published Online: November 29, 2011
... of the acinar duct would result in irreversible acinar flow fields, which might be important mechanistic contributors to aerosol mixing and deposition deep in the lung. Geometric hysteresis within the alveolar duct. ( a ) Case without surfactant. Geometric hystersesis is due to hysteresis of muscle...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2011, 133(6): 061004.
Published Online: June 21, 2011
...Emily J. Berg; Risa J. Robinson Emphysema is a progressive lung disease that involves permanent destruction of the alveolar walls. Fluid mechanics in the pulmonary region and how they are altered with the presence of emphysema are not well understood. Much of our understanding of the flow fields...
Journal Articles
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2010, 132(10): 101001.
Published Online: September 27, 2010
... the centerline is unknown and is found iteratively by extrapolation and assuming a parabolic distribution of velocity in the vicinity of the centerline. biodiffusion cellular biophysics flow simulation lung molecular biophysics numerical analysis physiological models pipe flow pneumodynamics...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. August 2010, 132(8): 081002.
Published Online: June 15, 2010
...Andrew Comerford; Christiane Förster; Wolfgang A. Wall In this paper, we develop structured tree outflow boundary conditions for modeling the airflow in patient specific human lungs. The utilized structured tree is used to represent the nonimageable vessels beyond the 3D domain. The coupling...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. May 2010, 132(5): 051009.
Published Online: March 30, 2010
...Sudhaker Chhabra; Ajay K. Prasad The alveoli are the smallest units of the lung that participate in gas exchange. Although gas transport is governed primarily by diffusion due to the small length scales associated with the acinar region ( ∼ 500 μ m ) , the transport and deposition of inhaled...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. May 2010, 132(5): 051010.
Published Online: March 30, 2010
...Sudhaker Chhabra; Ajay K. Prasad The acinar region of the human lung comprises about 300 × 10 6 alveoli, which are responsible for gas exchange between the lung and the blood. As discussed in Part I ( Chhabra and Prasad, “Flow and Particle Dispersion in a Pulmonary Alveolus—Part I: Velocity...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2010, 132(3): 031012.
Published Online: February 17, 2010
... , M. , and Robotham , J. L. , 1992 , “ Superior and Inferior Vena Caval Flows During Respiration: Pathogenesis of Kussmaul’s Sign ,” Am. J. Physiol. 0002-9513 , 262 ( 3 ), pp. H763 – H770 . Robotham , J. L. , and Takata , M. , 1995 , “ Mechanical Abdomino/Heart/Lung...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2010, 132(2): 021008.
Published Online: January 29, 2010
...Jessica M. Oakes; Steven Day; Steven J. Weinstein; Risa J. Robinson Particulates that deposit in the acinus region of the lung have the potential to migrate through the alveolar wall and into the blood stream. However, the fluid mechanics governing particle transport to the alveolar wall...
Journal Articles
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. January 2010, 132(1): 014501.
Published Online: December 8, 2009
.... Modifications first concerned the integration and interfacing of a user-controlled respiratory muscular system including intercostal muscles, scalene muscles, the sternocleidomastoid muscle, and the diaphragm and abdominal wall muscles. Volumetric and pressure measurement procedures for the lungs and both...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2009, 131(3): 031010.
Published Online: January 7, 2009
...Josué Sznitman; Thomas Heimsch; Johannes H. Wildhaber; Akira Tsuda; Thomas Rösgen The inhalation of micron-sized aerosols into the lung’s acinar region may be recognized as a possible health risk or a therapeutic tool. In an effort to develop a deeper understanding of the mechanisms responsible...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2009, 131(2): 021007.
Published Online: December 10, 2008
...C. Kleinstreuer; Z. Zhang A new methodology for a swift and accurate computer simulation of large segments of the human lung airways is presented. Focusing on a representative tracheobronchial (TB) region, i.e., G0–G15, nano- and micron particle transports have been simulated for Q in = 30 l ∕ min...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2009, 131(1): 011010.
Published Online: November 24, 2008
... incorporates key ingredients involved in these maneuvers: the expiratory effort generated by the abdominal and expiratory muscles, the glottis, and the flexibility and compliance of the lung airways. Variations in these allow investigation of the expiratory flows generated by a variety of single cough...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. January 2009, 131(1): 011006.
Published Online: November 19, 2008
... , A. , Rogers , R. A. , Hydon , P. E. , and Butler , J. P. , 2002 , “ Chaotic Mixing Deep in the Lung ,” Proc. Natl. Acad. Sci. U.S.A. 0027-8424 10.1073/pnas.102318299 , 99 , pp. 10173 – 10178 . Butler , J. P. , and Tsuda , A. , 1997 , “ Contribution of Convective...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2008, 130(3): 031020.
Published Online: May 9, 2008
... lung normal distribution physiological models pneumodynamics pulmonary pressure-volume curve respiratory system model alveolar recruitment lung injury ARDS In Ref. 9 , V U d is interpreted as the volume which would be attained if the elements that are open at the end...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. April 2008, 130(2): 021016.
Published Online: April 3, 2008
... of diffusing particles through the carousel effect. Ochs , M. , Nyengaard , J. R. , Jung , A. , Knudsen , L. , Voigt , M. , Wahlers , T. , Richter , J. , and Gundersen , H. J. G. , 2004 , “ The Number of Alveoli in the Human Lung ,” Am. J. Respir. Crit. Care Med...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2008, 130(1): 011015.
Published Online: February 20, 2008
... the dispersion and transport of therapeutic aerosols in the respiratory tract. A variety of mechanisms may contribute to convective dispersion in the lung; simple axial streaming, augmented dispersion, and steady streaming are investigated in this effort. Flow visualization of a bolus during inhalation...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2008, 130(1): 011013.
Published Online: February 11, 2008
... in bifurcating lung airways. But Nuckols ( 22 ) performed heat transfer studies in a two-generation symmetric model geometry and used a heat-mass transfer analogy to estimate the corresponding mass transfer coefficients. In a symmetric model of the first two tracheobronchial generations, the branch length...