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Keywords: cancer
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Journal Articles
Article Type: Review Articles
J Biomech Eng. October 2020, 142(10): 100804.
Paper No: BIO-20-1105
Published Online: August 31, 2020
...—in terms of their roles in health, aging, and diseases. References [1] Leight , J. L. , Drain , A. P. , and Weaver , V. M. , 2017 , “ Extracellular Matrix Remodeling and Stiffening Modulate Tumor Phenotype and Treatment Response ,” Annu. Rev. Cancer Biol. , 1 ( 1 ), pp. 313...
Journal Articles
Article Type: Research Papers
J Biomech Eng. August 2011, 133(8): 081006.
Published Online: September 6, 2011
...Simona Celi; Francesca Di Puccio; Paola Forte Among the available tools for the early diagnosis of breast cancer, the elastographic technique based on ultrasounds has many advantages such as the noninvasive measure, the absence of ionizing effects, the high tolerability by patients, and the wide...
Journal Articles
Article Type: Design Innovations
J Biomech Eng. February 2011, 133(2): 025001.
Published Online: January 5, 2011
... writing of human colon cancer cells (HT-29). The proposed four layers include a quartz disk, a sacrificial and adhesive layer, a metallic foil, and a cell suspension layer. The bubble formation-induced stress wave is responsible for droplet formation. It is found that the proposed metallic foil-assisted...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. October 2010, 132(10): 104501.
Published Online: September 10, 2010
...Sangjo Shim; Man Geun Kim; Kyoungwoo Jo; Yong Seok Kang; Boreum Lee; Sung Yang; Sang-Mo Shin; Jong-Hyun Lee In this paper, frequency response (dynamic compression and recovery) is suggested as a new physical marker to differentiate between breast cancer cells (MCF7) and normal cells (MCF10A...
Journal Articles
Article Type: Guest Editorial
J Biomech Eng. July 2009, 131(7): 070301.
Published Online: July 28, 2009
...Alptekin Aksan, Ph.D.; Allison Hubel, Ph.D.; John Bischof, Ph.D. biomembrane transport biothermics cancer molecular biophysics nanotechnology patient treatment proteins tumours 28 07 2009 Important applications of bioheat and mass transfer include biopreservation...
Journal Articles
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074003.
Published Online: July 28, 2009
... of selection, timing, dose and delivery of these adjuvants are then elaborated. Finally, work with a particularly promising vascular adjuvant, TNF-alpha, that shows the ability to destroy all cancer within a cryosurgical iceball is highlighted. References Hoffmann , N...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. July 2009, 131(7): 074519.
Published Online: July 16, 2009
...Devin McCormack; Mays Al-Shaer; Benjamin S. Goldschmidt; Paul S. Dale; Carolyn Henry; Chris Papageorgio; Kiran Bhattacharyya; John A. Viator Melanoma is the deadliest form of skin cancer and has the fastest growth rate of all cancer types. Proper staging of melanoma is required for clinical...
Journal Articles
Article Type: Technology Review
J Biomech Eng. July 2009, 131(7): 074001.
Published Online: July 16, 2009
...Emily S. Day; Jennifer G. Morton; Jennifer L. West Advances in nanotechnology are enabling many new diagnostic and therapeutic approaches in cancer. In this review, examples where nanoparticles are employed to induce localized heating within tumors are explored. Approaches to nanoparticle-mediated...
Journal Articles
Article Type: Research Papers
J Biomech Eng. July 2009, 131(7): 071006.
Published Online: July 16, 2009
... experienced a high electrical field, the axon of the nerve, the interior of the blood vessel, and the ducts experienced no electrical field. This indicates that blood vessels, nerves, and lactiferous ducts adjacent to a tumor treated with electroporation will survive, while the cancerous lesion is ablated...
Journal Articles
Article Type: Technical Briefs
J Biomech Eng. July 2009, 131(7): 074513.
Published Online: June 29, 2009
...Ka Yaw Teo; Bumsoo Han The efficacy of chemotherapy is significantly impaired by the multidrug resistance (MDR) of cancer cells. The mechanism of MDR is associated with the overexpression of certain adenosine triphosphate-binding cassette protein transporters in plasma membranes, which actively...
Journal Articles
Article Type: Research Papers
J Biomech Eng. July 2009, 131(7): 071003.
Published Online: June 5, 2009
... during HS abolished protection against apoptosis ( 20 ). Our data showed a very high basal HSP90 expression in hepatoma cells, which is consistent with the claim that high HSP90 concentration mediates the resistance to cytokines in cancer ( 21 ). The HSP90 contribute to the dynamic protection window...
Journal Articles
Article Type: Research Papers
J Biomech Eng. August 2008, 130(4): 041016.
Published Online: June 20, 2008
...Yusheng Feng; J. Tinsley Oden; Marissa Nichole Rylander The ultimate goal of cancer treatment utilizing thermotherapy is to eradicate tumors and minimize damage to surrounding host tissues. To achieve this goal, it is important to develop an accurate cell damage model to characterize the population...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. August 2007, 129(4): 548–557.
Published Online: December 6, 2006
... radiation therapy biological organs hyperthermia cancer tumours numerical analysis 14 01 2006 06 12 2006 Heat transfer which occurs in living tissue differs markedly from heat transfer in nonliving tissue or material. When living tissue is heated, blood flowing through the tissue...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. April 2007, 129(2): 129–136.
Published Online: September 21, 2006
...Zuoping Li; Neha B. Butala; Brandon S. Etheridge; Herrick J. Siegel; Jack E. Lemons; Alan W. Eberhardt Periacetabular bone metastases cause severe pain and functional disability in cancer patients. Percutaneous acetabuloplasty (PCA) is a minimally invasive, image-guided procedure whereby cement...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. February 2007, 129(1): 33–39.
Published Online: July 1, 2006
...Manu Mital; E. P. Scott Breast cancer is the most common cancer among women. Thermography, also known as thermal or infrared imaging, is a procedure to determine if an abnormality is present in the breast tissue temperature distribution. This abnormality in temperature distribution might indicate...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. December 2006, 128(6): 862–866.
Published Online: February 13, 2006
.... Lowering of the cooling rate decreases the excision force even if the temperature of the liver remains unchanged. The lower the temperature of the liver is, the larger the increment rate of excision force is with regard to the cooling rate. Since many liver cancer patients have cirrhosis...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. August 2006, 128(4): 505–515.
Published Online: February 3, 2006
...F. Scott Gayzik; Elaine P. Scott; Tahar Loulou Hyperthermia is a cancer treatment modality in which body tissue is exposed to elevated temperatures to destroy cancerous cells. Hyperthermia treatment planning refers to the use of computational models to optimize the heating protocol with the goal...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. August 2006, 128(4): 554–563.
Published Online: January 30, 2006
... ultrasonics patient treatment blood vessels vaporisation drops bubbles tumours cancer numerical analysis Microbubbles are relevant to a number of clinical situations including disease conditions, such as air embolism ( 1 2 3 4 5 6 7 8 9 10 ), and therapeutic and diagnostic...
Journal Articles
Article Type: Design Innovations
J Biomech Eng. April 2006, 128(2): 271–278.
Published Online: October 20, 2005
... adhesion tumours cancer haemorheology computational fluid dynamics capillarity hydrodynamics The purpose of this study was to develop a system capable of acquiring quantitative flow profiles over adherent cells. Experimental models that mimic the flow conditions in microcapillaries have...
Journal Articles
Article Type: Technical Papers
J Biomech Eng. December 2004, 126(6): 745–759.
Published Online: February 4, 2005
...Tao Ye; Joseph L. Bull We are currently developing a novel gas embolotherapy technique that involves the selective, acoustic vaporization of liquid perfluorocarbon droplets in or near a tumor as a possible treatment for cancer. The resulting bubbles can then stick within the tumor vasculature...