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Keywords: aerosols
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Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. November 2011, 133(11): 111005.
Published Online: November 29, 2011
...M. Kojic; J. P. Butler; I. Vlastelica; B. Stojanovic; V. Rankovic; A. Tsuda Low Reynolds number airflow in the pulmonary acinus and aerosol particle kinetics therein are significantly conditioned by the nature of the tidal motion of alveolar duct geometry. At least two components of the ductal...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. May 2010, 132(5): 051009.
Published Online: March 30, 2010
... aerosol particles are influenced by convective airflow patterns. Therefore, understanding alveolar fluid flow and mixing is a necessary first step toward predicting aerosol transport and deposition in the human acinar region. In this study, flow patterns and particle transport have been measured using...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2010, 132(2): 021008.
Published Online: January 29, 2010
... are not well understood. Many physiological conditions are suspected to influence particle deposition including morphometry of the acinus, expansion and contraction of the alveolar walls, lung heterogeneities, and breathing patterns. Some studies suggest that the recirculation zones trap aerosol particles...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2009, 131(3): 031010.
Published Online: January 7, 2009
...Josué Sznitman; Thomas Heimsch; Johannes H. Wildhaber; Akira Tsuda; Thomas Rösgen The inhalation of micron-sized aerosols into the lung’s acinar region may be recognized as a possible health risk or a therapeutic tool. In an effort to develop a deeper understanding of the mechanisms responsible...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2008, 130(1): 011015.
Published Online: February 20, 2008
... the dispersion and transport of therapeutic aerosols in the respiratory tract. A variety of mechanisms may contribute to convective dispersion in the lung; simple axial streaming, augmented dispersion, and steady streaming are investigated in this effort. Flow visualization of a bolus during inhalation...
Journal Articles
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. February 2008, 130(1): 011008.
Published Online: February 7, 2008
...Jinxiang Xi; P. Worth Longest The deposition of ultrafine aerosols in the respiratory tract presents a significant health risk due to the increased cellular-level response that these particles may invoke. However, the effects of geometric simplifications on local and regional nanoparticle...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2007, 129(5): 722–732.
Published Online: February 18, 2007
...Frank E. Fresconi; Ajay K. Prasad An understanding of flow and dispersion in the human respiratory airways is necessary to assess the toxicological impact of inhaled particulate matter as well as to optimize the design of inhalable pharmaceutical aerosols and their delivery systems. Secondary flows...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2007, 129(1): 51–57.
Published Online: June 30, 2006
... of Pollution From the Great Lakes ,” Science 0036-8075 10.1126/science.155.3767.1242 , 155 ( 3767 ), pp. 1242 – 1243 . McCawley , M. , Abrons , H. , and Lippmann , M. , 1988 , “ Modelling an Aerosol Dispersion Test for Detecting Early Airway Changes ,” Ann. Occup. Hyg. 0003-4878...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2004, 126(5): 604–613.
Published Online: November 23, 2004
...G. M. Allen; B. P. Shortall; T. Gemci; T. E. Corcoran; N. A. Chigier In order to understand mechanisms of gas and aerosol transport in the human respiratory system airflow in the upper airways of a pediatric subject (male aged 5) was calculated using Computational Fluid Dynamic techniques...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. April 2003, 125(2): 197–206.
Published Online: April 9, 2003
...C. Kleinstreuer; Z. Zhang One important research area of broad interest is the development of highly efficient drug delivery systems for desired site deposition and uptake. For example, controlled drug aerosol release and targeting to specific regions of the lung is a novel way to combat lung...
Journal Articles
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. December 2002, 124(6): 629–637.
Published Online: December 27, 2002
... have important effects on aerosol deposition within the throat. There is no correspondence noted between regions of high axial turbulence intensity and deposition. Contributed by the Bioengineering Division for publication in the JOURNAL OF BIOMECHANICAL ENGINEERING . Manuscript received November...