Spine stiffening or also called Ankylosing Spondylitis (AS) is a type of progressive arthritis that leads to a chronic inflammation affecting spinal column and sacroiliac joints (SI). Long-term inflammation of the spinal joints (called Spondylitis) leads to calcium deposits forming on the ligaments and around the intervertebral discs. Subsequent tissue inflammation resulted from deposition of calcium, causes the spine to stiffen and potential mobility loss. This may result in clinical sequelae such as long-term disability and in complete fusion of vertebral column (Ankylosis) in severe cases . Current literature on AS and its effects on segmental biomechanics is not known. Hence, this study designed to investigate the biomechanical effects of spine stiffening through changing the stiffness of soft tissue (ligaments & discs) across lumbar spine using finite element (FE) analysis.
- Bioengineering Division
Effects of Spine Soft Tissue Stiffening on Biomechanics of Lumbar Spine: A FEA Study
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Kiapour, A, Kiapour, AM, Goel, VK, & Sairyo, K. "Effects of Spine Soft Tissue Stiffening on Biomechanics of Lumbar Spine: A FEA Study." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT09A023. ASME. https://doi.org/10.1115/SBC2013-14664
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