Obtaining bone mechanical properties from clinical resolution quantitative computed tomography (QCT)-derived localized apparent density presents the most attractive, available tool for developing subject-specific finite element (FE) bone models. While QCT density is a good predictor of the mechanical properties of HVTB [1, 2], knowledge of the fabric tensor (anisotropy ratio) can substantially improve prediction  and accuracy of CT-based continuum FE models . Unfortunately, resolution of currently available clinical CT scanners is inadequate for mapping the fabric tensor of HVTB, which is known to be at least transversely isotropic . Furthermore, trabecular bone mechanical anisotropy ratio has been shown to vary with density .
- Bioengineering Division
Dependence of Human Lumbar Vertebral Trabecular Bone (HVTB) Mechanical Anisotropy Ratio on QCT–Based Apparent Density
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Aiyangar, A, Vivanco, J, Au, A, Anderson, P, Smith, E, & Ploeg, H. "Dependence of Human Lumbar Vertebral Trabecular Bone (HVTB) Mechanical Anisotropy Ratio on QCT–Based Apparent Density." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT09A014. ASME. https://doi.org/10.1115/SBC2013-14274
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