This paper investigates the effect of superimposed length oscillation (SILO) on tidal breathing on contracted airway smooth muscle (ASM) relaxation. The combined effect of SILO with each one of four inhibitors (Isoproterenol, Indomethacin, PD0980590 and SB 203580) is investigated to explore the molecular pathways involved in the tissue relaxation process.
- Bioengineering Division
An Investigation Into the Molecular Pathways of Airway Smooth Muscle Relaxation
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Al-Jumaily, AM, Koumba, N, Avila, MJ, & Roos, K. "An Investigation Into the Molecular Pathways of Airway Smooth Muscle Relaxation." Proceedings of the ASME 2013 Summer Bioengineering Conference. Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments. Sunriver, Oregon, USA. June 26–29, 2013. V01AT05A002. ASME. https://doi.org/10.1115/SBC2013-14025
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