Analysis of blood as a two phase flow of densely packed finite size particles is a challenging problem that requires a numerical approach that can efficiently and accurately handle large numbers of objects moving through a fluid. Numerical schemes such as the Arbitrary Lagrangian-Eulerian method (ALE), Distributed Lagrangian Multiplier (DLM) or the Immersed Boundary Method (IBM) are useful for simulating particulate flows. However, in the development of a multiscale framework where the dynamics of particles may be evolved at different scales, these methods may be too expensive for the desired resolution.
- Bioengineering Division
Implementation of Smoothed Profile Modeling in Two Phase Flow Analysis of RBCs in Blood
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Mohaghegh, F, Udaykumar, HS, Mousel, J, Chivukula, V, & Chandran, KB. "Implementation of Smoothed Profile Modeling in Two Phase Flow Analysis of RBCs in Blood." Proceedings of the ASME 2012 Summer Bioengineering Conference. ASME 2012 Summer Bioengineering Conference, Parts A and B. Fajardo, Puerto Rico, USA. June 20–23, 2012. pp. 1311-1312. ASME. https://doi.org/10.1115/SBC2012-80508
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