Application of thermal therapy using microwave or ultrasound applicators is becoming increasingly popular as a minimally invasive treatment for benign prostatic hyperplasia (BPH). Successful management of the therapy using such methods requires an accurate estimation of the thermal dosage. The purpose of this study is to theoretically evaluate the thermal damage caused by different heating sources for different values of thermal doses and operating parameters. Using a 3-D finite differences method, the Pennes bio-heat transfer equation is solved for selected operating parameters. Necrosis zones are then determined from published necrosis data for prostatic tumor cells. Sample results are presented in terms of the temperature contours and necrosis zones. Results indicate that heating time and power level are the most important parameters in creating the desired necrosis zones, while coolant parameters strongly affect the temperatures of the sensitive urethra and serve as constraints for protocol parameters.
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ASME 2005 International Mechanical Engineering Congress and Exposition
November 5–11, 2005
Orlando, Florida, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
0-7918-4213-4
PROCEEDINGS PAPER
Treatment Protocols for Managing Transurethral Thermal Therapy for Benign Prostatic Hyperplasia
Chandrasekhar Thamire
Chandrasekhar Thamire
University of Maryland
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Lara Paolini
University of Maryland
Chandrasekhar Thamire
University of Maryland
Paper No:
IMECE2005-81421, pp. 75-76; 2 pages
Published Online:
February 5, 2008
Citation
Paolini, L, & Thamire, C. "Treatment Protocols for Managing Transurethral Thermal Therapy for Benign Prostatic Hyperplasia." Proceedings of the ASME 2005 International Mechanical Engineering Congress and Exposition. Advances in Bioengineering. Orlando, Florida, USA. November 5–11, 2005. pp. 75-76. ASME. https://doi.org/10.1115/IMECE2005-81421
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